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| methonal |
5incere |
09/14/06 |
explanation of why treating methanol poisoning with ethanol lowers the death rate. |
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saugy
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09/14/06 |
Dear Sincere - Ingestion of ethanol interferes with the conversion of methanol to its toxic metabolites by the liver (methanol itself is not toxic; it is the metabolites formaldehyde and formic acid that do the damage). See http://www.anaesthesiamcq.com/AcidBaseBook/ab8_6a.php and http://www-clinpharm.medschl.cam.ac.uk/pages/teaching/topics/poison/poison9.html for more detailed information.
Hope this helps, Saugy |
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